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Montelukast for AD
Has anyone's doctor mentioned Montelukast as treatment for AD. I have read some studies showing it has a positive effect on the inflammation reaction in the brain?
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Gene therapy shows promise for Alzheimer’s disease
Gene therapy shows promise for Alzheimer’s disease San Diego VA researchers demonstrated in mouse models that targeting specific brain neurons through gene therapy in early-stage Alzheimer’s disease may help preserve memory and stimulate neuron growth. The researchers focused on the protein Cav-1, which promotes the growth…
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How to help with dementia and sundowners
I am new to all this. I worked in a dementia care unit as a companion but it is nothing compared to feeling so helpless when it comes to my grandma. My dad wants to put her in a home and I gave her my word I would not let that happen. It breaks my heart seeing her decline and not know who I am. I had never even heard of…
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Clarity VS deep sleep or unresponsiveness
My 91 year old mother has vascular dementia and shows a pattern of two days of clarity and sleeps for 3 days nonstop and back at clarity again. This has been a pattern since Jan 2025. She was diagnosed in 2020 and lives in a Care Center Facility. Is any of your love ones with vascular dementia going through this cycle?
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Rapid progressing AD because of seizures???
Hi everyone, My mom is in her late 60's. She was diagnosed with mild dementia about a year and a half ago. She has been having seizures and it seems to be progressing the dementia at a very rapid rate. They're now saying she's got Moderate dementia, which seems accurate based on what we're seeing and the level of care…
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Warning: Avoid Brain Injury in mAb Clinical Trials.
In 2023, I was in a clinical trial similar to those mentioned in the NY Times article posted here by Crushed. (Alzheimer's drug horror story from the NYT, posted 10/23/2023). I was tested and accepted into the study in January. After taking 5 doses, one injection each week for five weeks, I started getting side effects. I…
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Filing for Long Term Care Insurance too early?
Hi, I am posting for the first time regarding my 83 year old Grandma. She has had cognitive and memory issues for years, but in the past month she was properly diagnosed with dementia. I had previously lived with her 3 years ago after she was a scam victim, but after about a half of year, I moved back home. I am now…
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New Treatment?
Hello, I recently read about studies using Benfotiamine to treat early AD and MCI. It seems to work. According to the NIH "Results: Participants were treated with benfotiamine (34) or placebo (36). Benfotiamine treatment was safe. The increase in ADAS-Cog was 43% lower in the benfotiamine group than in the placebo group,…
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60 minutes interview
This was posted by a neighbor. Can you imagine being worried about retaliation for speaking about Alzheimer’s research?
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Took part in Alzheimers Research study
My father clearly had some form of dementia but didn't get an actual diagnosis, it was just described as senile dementia. I have never had a great memory, but it was getting worse. I recently participated in a research study looking for the biomarker for Alzheimers. Blood tests showed I have the biomarker for Alzheimers.…
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Doctored: Fraud, Arrogance, and Tragedy in the Quest to Cure Alzheimer's
Been hearing a lot about this book recently through podcasts and interviews with the author. Very important to know about this misconduct in the Alzheimer's research field. It's so discouraging to know this is happening. Doctored: Fraud, Arrogance, and Tragedy in the Quest to Cure Alzheimer's…
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Bredesen randomized controlled trial
I recently listened to an interview on People’s Pharmacy with Dale Bredesen. He mentioned that he is the study chair for a randomized controlled trial for his approach to addressing a treatment approach for MCI or early stage dementia. Here’s a link to the page with more info about the trial…
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Compassionate Use or Expanded Access options
Is anyone getting any therapies through Compassionate Use or Expanded Access programs? I saw a comment from someone in a Facebook group who was considering TB006 a compound being developed by True Binding. So it made me wonder if anyone here has considered it or other experimental options that are in development.
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Lecanemab 3 year data
We listened to a presentation the other day by doctor at Duke University. He mentioned there is 3 year data now on lecanemab. He presented the info in a support group for those who are getting lecanemab or who may be interested in getting it. Open Label Extension Data Shows Lecanemab’s Continued Effect on Alzheimer Disease…
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New research on the timeline of Alzheimer's
Research is being called "ground breaking" Alzheimer’s May Progress in Two Phases, Transforming Understanding of Brain Damage - CogniFit Blog: Brain Health News
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Moderate Sedation with MCI
I’m 51 and scored in the MCI range on a recent cognitive screening when I told a neurologist I felt like I had memory issues. The cause is still being determined. Initial blood tests show it’s likely not Alzheimer’s, though I still have an MRI and sleep eeg. That said, my mother has Alzheimer’s, as likely my paternal…
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Zunveyl new med on the horizon
I came across some info about this medication today. It just received FDA approval in July 2024 and is predicted to be on the market in early 2025. I'm very curious about it because my wife has been taking rivastigmine and has been having a horrible time with the nausea side effect. I also read this study that was posted…
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Participated in a study
We participated in this study today. My wife, who has MCI with Azlheimer's pathology, is very interested in participating in research and signed up for a couple of non-drug related opportunities. We both participated in this one. Pretty cool and easy and we earned some money for it too. Qualitative Analysis of the Content…
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Good review article M1 receptor targeting
I came across this good review article from 2022 when I was looking for things to help my wife who is experiencing adverse effects from donepezil and rivastigmine. It’s a good review article of the progress being made to develop drugs that have less adverse effects. Doesn’t look like anything is coming on the market…
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National Academies’ Forum GLP-1R agonists
This discussion is open to the public and there is an option for attending virtually This is the class of meds that are being used for diabetes and weight loss. They are exploring their affect on neurodegenerative diseases…
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Intelgenx shows cognitive improvement
In April I posted here about the Emory University montelukast Alzheimer's trial. The trial results showed that one group of participants showed cognitive improvement. However the results were suspect because the group showing improvement was the placebo group. The group supposedly treated with montelukast continued to…
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Electroconvulsive therapy (ECT)
I’ve recently discovered that some patients with dementia may be treated with ECT in the hopes that it will improve symptoms of depression. Does anyone have experience with this that you can share? Here’s just one article I found about it
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NY Times: How Hearing and Vision Loss Increase the Risk of Dementia
Gifted article for 30 days https://www.nytimes.com/2024/08/08/well/mind/hearing-vision-dementia-risk.html?unlocked_article_code=1.Bk4.olZa.vDIdaqXHJqa1&smid=url-share
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Virtual Reality Experience
has anyone had any positive experiences using VR headsets with their loved ones?
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lost
Hi I am new to ALZCONNECTED im not sure where to start. my mom has been diagnose with AlZ. she currently lives with my dad, but my dad is having a really difficult time accepting her diagnosis. he is not willing to educate himself about the disease and has no patience for my mom. he keeps saying he can't go through with…
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Early Stages: assessment, support, education
Hello, I am in the early stages of needing to get my LO a neurological assessment and get educated as their child on the best ways to support them moving forward. It's hard to know if they are in early stages or if aging and isolation and depression are the culprits. (want to acknowledge that i know they will exacerbate…
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Feeling frustrated
I am new to the community. My mom is 77 years old. She has not been diagnosed with dementia but definitely can tell her cognitive skills are not up to par. She thinks things around house are turning black,blames my Dad for all of it(inside & outdoor plants,floors,cabinets,etc),wipes floors and cabinets with olive oil. She…
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Nanny Cam vs. Security Cam
Hi all, so the topic of installing cameras has come up many times as a means to keep an eye on my folks and the certified aides. Dad vocalized not wanting them on grounds of his privacy being invaded which I understand. However, it’s just getting more & more concerning with aides being lazy, falling asleep, and mom growing…
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Caregivers Support by Participating in a New Study
Hello! I am new to all of this, only have had experience with dementia and Alzheimer's when both my Grandmother and my husband's Grandmother were diagnosed many years ago. We just learned my Mom's results of recent neurology tests, and all of this is overwhelming. I feel helpless, especially living 3+ hours from the rest…