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donepezil

My HWD has been taking donepezil for over a year…he refused to take it over the weekend because he said that his dr told him to stop (not true) and that I didn't know what I was talking about and was trying to poison him. I messaged our doctor (unfortunat

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  • Bailey's Mom
    Bailey's Mom Member Posts: 213
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    Sorry…pushed send in error. (unfortunately it was the weekend and she couldn't be reached. Yesterday his dr messaged back and told him to continue taking it, and he has. While he was not taking it he was nicer (he is an angry, mean person by nature) but since he has gone back on donepezil he has been horrible…agitated, confused and blaming me for everything. I was wondering if others have had a similar experience with this drug?

  • Linb
    Linb Member Posts: 9
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    That is not a good sign for sure. My DH is a kind, gentle person by nature, but that is gradually changing to anger (not to me yet), confusion, fear and forgetfulness. He has almost panic attach's if I leave the house. I will tell him I'm going to the store and he will say, ok, then ask where I have been when I get back. This is new to us so we have a lot to learn……patience for sure. Thank you for responding. I hope others do too.

  • jgreen
    jgreen Member Posts: 287
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    Hi @Bailey's Mom,

    My DH was prescribed donepezil to help with sundowning. It has helped for a while, but now he’s seeing things and talking more in his sleep.

    What I read online was to see if you can keep DH more active during the day, get out in natural light whenever possible, have better lighting to reduce shadows, and try to stick to a routine to help reduce anxiety. The literature also says it is not a cure, so I am not sure if missing doses or stopping the drug altogether is a bad thing.

    We have first Neuro appt in early January and I hope it will include a review of all his meds. Maybe some adjustments are in order. Let us know what your doctor says about your DH.

    Hang in there! Sending you a warm hug!💝

  • Quilting brings calm
    Quilting brings calm Member Posts: 3,109
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    Donepezil is helpful for 1 in 10, has too many side affects for 1 in 10, and is neutral for the rest. My mom couldn’t get beyond the lowest dose of it because it was too hard on her gastrointestinal system. There’s really no clear picture on whether it delays symptoms or not. The progress is still happening behind the scenes regardless, and the speed varies from person to person. Whether or not he takes is not something I’d choose to argue over.

  • SDianeL
    SDianeL Member Posts: 3,175
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    I would speak to the doctor and be specific about the behaviors. Perhaps they could change the medication. A geriatric psychiatrist is the best type of doctor to manage meds for dementia patients.

  • harshedbuzz
    harshedbuzz Member Posts: 6,293
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    @Bailey's Mom

    Donepezil is prescribed to help PWD "function better". It is not a cure; the disease continues to ravage the brain regardless.

    Reading other posts of yours, I've always had a sense that your DH and my dad were cut from very similar cloth. Our PWD was angry, bitter and mean as a baseline making the middle stages very difficult for my mom. As he progressed deeper into late stage 6 and 7, he seemed to lose that edge. By the last month of his life he'd regressed to "the sweet little boy" his doting aunts always described— he became warm and affectionate. YMMV, but fingers crossed it is similar for you.

    I know mom and I would not have made a decision to continue any medication that preserved his ability to hold on to the negative emotions driving his ghastly behavior. Is he seeing a geri psych? Dad's was, after mom, the most important person on dad's team.
    HB

  • Bailey's Mom
    Bailey's Mom Member Posts: 213
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    Harshedbuzz…his PCP made a referral for geri-psych, but they wouldn't accept his insurance and I haven't been able to find one that does yet. Not alot of quality dementia relatedresources available in my area. Still trying, though, as his PCP is about out of ideas for him.

  • Bailey's Mom
    Bailey's Mom Member Posts: 213
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    I sure hope he gets over his angry, mean stage as he progresses, but he has always had this kind of personality, so may not!

  • Cardenas1816
    Cardenas1816 Member Posts: 34
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    I’m having the same trouble finding a geriatric psychiatrist. All of the ones that do take our insurance aren’t taking new patients. Wondering if any of you have experience with telemedicine geriatric psychiatrists?

  • harshedbuzz
    harshedbuzz Member Posts: 6,293
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    You may have difficulty finding a geri psych outside of a teaching hospital memory center that takes your insurance. Psychiatrists often don't accept insurance. I've always paid out-of-pocket for my son's psychiatrists as neither took insurance. Dad's did take insurance, but mom's psychiatrist does not accept her insurance.

  • aglita
    aglita Member Posts: 8
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    my DH sees a geriatric psych by telemedicine it is very hard where we live to find geriatric psychiatrists. This is his 2nd one due to his other closing her practice not sure this one is the right fit though changed his meds around and he’s much worse on these new meds

  • Bailey's Mom
    Bailey's Mom Member Posts: 213
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    Unfortunately, my HWD could never manage a telemedicine appt…he would not understand what the psych was saying and would probably pretend that he did and then come up with a completely different story about what actually happened. His PCP convinced him to start taking donepezil again…he also takes zoloft, although I'm not sure if that makes him better or worse. Would be interested in hearing how your DH does with the telemedicine visits…

  • tboard
    tboard Member Posts: 252
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    My DH often refuses his medications. I show him the bottle with his name on it and explain that the pills are the doctors idea not mine. If the donepezil is causing meanness let his doctor know.

  • Victoriaredux
    Victoriaredux Member Posts: 154
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    If his behavior changes are sudden have you had him checked for a UTI? I'd also try to downplay the taking of the pills - take yours with him - even if sugar pills -and call them vitamins.

    Decisions or thinking they have to make a decision about pills throws PWD for a loop sometimes and then they resist to avoid the stress of a decision their brain can no longer process. You maybe be stressed and worried about getting the meds in him and he feels that anxiety

  • Linb
    Linb Member Posts: 9
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    Thank you for commenting.

  • Linb
    Linb Member Posts: 9
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    Thank you…very informative.

Commonly Used Abbreviations


DH = Dear Husband
DW= Dear Wife, Darling Wife
LO = Loved One
ES = Early Stage
EO = Early Onset
FTD = Frontotemporal Dementia
VD = Vascular Dementia
MC = Memory Care
AL = Assisted Living
POA = Power of Attorney
Read more