New clinical trial for MCI

This is not a "new trial". Per the article, the AHEAD trial finished their enrollment in October 2024, and it is a four-year trial. So around late 2028, they should start to get results from the trial. The idea is that starting Leqembi very early, before any cognitive decline, may result in amyloid clearance with the result that cognitive decline may be prevented. In simple terms, you might consider this a cure for AD, if this strategy works. Hence the title for the article "The AHEAD Study: Can Alzheimer's Be Prevented or Slowed Before Symptoms Begin?"

Hi LBC83, (and anyone else willing to share Leqembi experiences)

Totally off subject, but you noted that you just completed your 40th Leqembi infusion. (wow, congrats!!) I am curious how you feel it has or not helped with your cognitive abilities. I am about to take my 6th infusion and I am amazed at the sense of clarity+ I feel. I have been a few years feeling as if I was thinking through thick fog... if that makes sense. I cannot think of another way of explaining. It feels, with the last few infusions that I have gained significant mental clarity.... Memory that has been lost is still gone but my clarity of thought processing has increased greatly. For example I regularly meet with a group of about 7 friends for supper. For the last probably two years I have been unable to follow the conversations had round the table nor have I been able to contribute to them. However, the most recent meetup, was significantly different. I am also an artist and have always made my Christmas presents... but for the last couple years because I did not make any because I could not find my "inspiration". However, this year, I was able to find my inspiration and I just realized why. For the last two + years I was not able to "see my minds eye"...My "minds eye" was solid black, no images, colors, no visual memories etc. I could not imagine in my minds eye what my art project was going to look like and therefore I could not create. BUT!!! This year I could... It was miraculous!! Have you (or anyone else reading this) had any similar improvements from Leqembi infusions and if so, does it just get better and better the longer I am on it? I realize that the brain cells that have died due to the plaque will not return but will I continue to see improvements or will they start leveling off etc. (Sorry for going on so long. Thanks for listening)

GE

Thank you for sharing your experience with the infusions. I am scheduled to start Kisunla infusions this month. I am still feeling quite concerned about getting the infusions. I would like to see more people share their experience with the infusions.