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Antipsychotics Lead to Dementia; New Research Illuminates Why

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  • Crushed
    Crushed Member Posts: 1,442
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    Michael Ellenbogen wrote:

    this is dementia as a SYMPTOM and not the same as Alzheimer's 

    we know this because it says

    “These results have been confirmed in randomized clinical trials showing cognition improves when antipsychotic dosage is reduced.”

     Many drugs depress cognition while you take them  

    CDC Dementia is not a specific disease but is rather a general term for the impaired ability to remember, think, or make decisions that interferes with doing everyday activities

  • Lane Simonian
    Lane Simonian Member Posts: 348
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    Thank you for the article, Michael.  While more work needs to be done on this, I found the following passages from the article well-worth considering:

    "Antipsychotic exposure has been linked to worse cognition in both cross-sectional and longtitudinal observation studies," the researchers write. "These results have been confirmed in randomized clinical trials showing cognition improves when antipsychotics dosage is reduced."

    The researchers note that antipsychotics have also been found to cause cortical thinning and loss of gray matter and that studies have concluded that this is not due to the underlying “illness” but to the drug’s impact on the brain. "This association is not explained by illness duration or symptom severity, suggesting that antipsychotic exposure itself drives coritical loss," they write.  

Commonly Used Abbreviations


DH = Dear Husband
DW= Dear Wife, Darling Wife
LO = Loved One
ES = Early Stage
EO = Early Onset
FTD = Frontotemporal Dementia
VD = Vascular Dementia
MC = Memory Care
AL = Assisted Living
POA = Power of Attorney
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