Have any questions about how to use the community? Check out the Help Discussion.

Monoclonal antibody not effective in pre-clinical Alzheimer’s Disease. NEJM

Comments

  • M1
    M1 Member Posts: 6,788
    1,500 Care Reactions 1,500 Likes 5000 Comments 1,000 Insightfuls Reactions
    Member

    Thanks Marta, very important article. I'm going to see if an editorial accompanied it and will post if I find it.

  • Jo C.
    Jo C. Member Posts: 2,952
    Legacy Membership 2500 Comments 250 Likes 100 Care Reactions
    Member

    Very, very interesting Marta; thank you for sharing that article, that trial is certainly significant in its findings. Wonder if the study participants were all one gender or if both genders were included.

    M1; thank you also for looking for an editorial; I will keep looking here to see if it was found. (I no longer have access to the NEJM,)

    J.

  • Iris L.
    Iris L. Member Posts: 4,479
    Legacy Membership 2500 Comments 500 Likes 250 Care Reactions
    Member

    I wonder how they determined who had elevated beta-amyloid levels without evidence of cognitive impairment?

    Iris

  • M1
    M1 Member Posts: 6,788
    1,500 Care Reactions 1,500 Likes 5000 Comments 1,000 Insightfuls Reactions
    Member

    No editorial. Iris these folks were mostly being followed because of a family history of dementia (75%). 60% of the study participants were women.

  • Iris L.
    Iris L. Member Posts: 4,479
    Legacy Membership 2500 Comments 500 Likes 250 Care Reactions
    Member

    But that doesn't answer the beta-amyloid question.

    Iris

  • Marta
    Marta Member Posts: 694
    Legacy Membership 500 Comments 100 Likes 25 Care Reactions
    Member
    edited September 2023

    Iris - beta amyloid PET scanning was performed.

  • Iris L.
    Iris L. Member Posts: 4,479
    Legacy Membership 2500 Comments 500 Likes 250 Care Reactions
    Member

    I see. Thanks for solving that question for me, Marta, because otherwise it made no sense.

    Iris

Commonly Used Abbreviations


DH = Dear Husband
DW= Dear Wife, Darling Wife
LO = Loved One
ES = Early Stage
EO = Early Onset
FTD = Frontotemporal Dementia
VD = Vascular Dementia
MC = Memory Care
AL = Assisted Living
POA = Power of Attorney
Read more