Monoclonal antibody not effective in pre-clinical Alzheimer’s Disease. NEJM

Marta

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M1

Thanks Marta, very important article. I'm going to see if an editorial accompanied it and will post if I find it.

Jo C.

Very, very interesting Marta; thank you for sharing that article, that trial is certainly significant in its findings. Wonder if the study participants were all one gender or if both genders were included.

M1; thank you also for looking for an editorial; I will keep looking here to see if it was found. (I no longer have access to the NEJM,)

J.

Iris L.

I wonder how they determined who had elevated beta-amyloid levels without evidence of cognitive impairment?

Iris

M1

No editorial. Iris these folks were mostly being followed because of a family history of dementia (75%). 60% of the study participants were women.

Iris L.

But that doesn't answer the beta-amyloid question.

Iris

Marta

Iris - beta amyloid PET scanning was performed.

Iris L.

I see. Thanks for solving that question for me, Marta, because otherwise it made no sense.

Iris