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PET Scan Amyloid results

DWofDH
DWofDH Member Posts: 21
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DH just had amyloid pet scan. Just reaching out to see if anyone has any insight on where he might be with all of this based on the widespread findings. Findings were:

"Tracer activity is noted in the brainstem and cerebellar peduncles but not in the cerebellar hemispheres. Tracer activity is noted in the frontal, parietal, temporal and occipital lobes. The Centiloid value is 84.98."

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  • Dio
    Dio Member Posts: 786
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    What did the doctor say? I'm not a doctor, but when my DH got the Petscan, the dr was specifically looking for amyloid to determine whether it was Alzheimer's. Since there was no trace, he ruled out AD. Hope you get a clear picture/diagnosis from your dr.

  • DWofDH
    DWofDH Member Posts: 21
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    Nothing yet. I just got the report from the radiologist. There is amyloid plaque in all of those areas. It is very widespread.

  • Timmyd
    Timmyd Member Posts: 78
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    This is how our report read. My DW has progressed significantly since then:

    FINDINGS:

    There is no evidence for motion/misregistration between the PET and CT images.

    The CT portion of the examination demonstrates no evidence for intra-or extra-axial masses, fluid
    collections, hemorrhage, hydrocephalus, mass, mass effect, or acute cortical infarction. There is no
    atrophy.

    The PET images demonstrate normal physiologic uptake of radiotracer throughout the white matter.
    There is abnormal retention of radiotracer in the cerebral gray matter. The gray matter activity is therefore
    equal to or greater than white matter activity, resulting in a loss of normal gray-white matter contrast.

    PET/CT
    IMPRESSION:
    Abnormal scan indicating moderate to frequent amyloid neuritic plaques in an amount that has been
    shown to have significant correlation with Alzheimer's Disease. This finding has; however, been
    demonstrated in other neurological conditions, or as a variant of extreme old age, therefore clinical
    correlation is needed.

  • DWofDH
    DWofDH Member Posts: 21
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    Thank you for sharing. What has the timeframe of progression been? I worry that it is in his brainstem.

  • SDianeL
    SDianeL Member Posts: 1,471
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    edited April 28

    here’s what AI says: https://grok.com/?q=%22Tracer+activity+is+noted+in+the+brainstem+and+cerebellar+peduncles+but+not+in+the+cerebellar+hemispheres.+Tracer+activity+is+noted+in+the+frontal%2C+parietal%2C+temporal+and+occipital+lobes.+The+Centiloid+value+is+84.98.%22

  • Timmyd
    Timmyd Member Posts: 78
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    My DW progression has been described as "typical" When diagnosed in in early 2022 she was described as late 4 / early 5. She is now early 6, maybe even middle 6.

Commonly Used Abbreviations


DH = Dear Husband
DW= Dear Wife, Darling Wife
LO = Loved One
ES = Early Stage
EO = Early Onset
FTD = Frontotemporal Dementia
VD = Vascular Dementia
MC = Memory Care
AL = Assisted Living
POA = Power of Attorney
Read more