Neuropsych Assessment/role in diagnosis
Husband with recent diagnosis of mild cognitive impairment based on assessments given by PCP & neurologist. Definitely struggling with executive functioning, short term memory and word finding/communication. MRI showed nothing out of the ordinary for his age. Did make note of a gilial scar on frontal lobe but indicated it was of no clinical significance.
Our next appointment is a referral to a neuropsychologist for a 4-5 hour assessment. Just wondering for those that have been through this assessment, what information did it yield? I walked away from the neurologist appointment feeling like this is just another box to check.
Appreciate your thoughts.
Comments
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That was our journey. First PCP who said it was just menopause ( my DW was 52 at that time), then referral to neurologist who concluded brain scan was normal for her age, then referral to neuropsychologist for the 4+ hour assessment. Neuropsychologist diagnosed her with Primary Progressive Aphasia. I still wasn’t convinced that was it totally so had to go out of network on my dime to Mayo Clinic in Minnesota. After a week of testing official diagnoses of Early Onset Alzheimer’s disease. She was 53 at that time. Keep pushing until you’re satisfied with the answer.
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yes, I really feel like in this disease/condition space, we do have to be more vigilant for answers.
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…Our next appointment is a referral to a neuropsychologist for a 4-5 hour assessment - For my DW age 49, not only was this the test where she was able to really understand her own decline but it was used by SS for her disability claim. We have had all the other testing but this one was important in our journey.
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The neuropsychologist assessment was when we received a definitive diagnosis. The PCP reviewed my husband’s MRI and said it reflected normal aging. I told the PCP that I felt it was more than normal aging and without any resistance he referred us to a neurologist. After speaking with my husband for a few minutes the neuro referred us to the neuropsych for a MoCA Blind since the assessment was by phone appointment. At the end of the call we were given the diagnosis of dementia of the ALZ type. At that time, August 2025, he was stage 4. We didn’t request further testing or assessments once we received the diagnosis.
I’m sorry for your need to be “here” but glad you found this community of supportive, caring and knowledgeable people.2 -
Thank you your reply. I’m glad to hear this is where you were able to find answers.
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Appreciate your reply. We are in that space as well. MRI looked ok given his age yet something is not right. I’m glad to hear that the neuropsychologist assessment provided clarity. I’m glad our neurologist has referred us for this next step.
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I agree with others that the neuropsychologist's testing was critical for a diagnosis. The testing is in depth and covers all parts of brain functioning. The results will tell you specifically what parts of the brain have been impacted resulting in loss of function and how this will impact every day functioning with your loved one. You didn’t mention a PET scan of the brain. I would ask for this test as well. This is a standard test ordered by a neurologist to diagnose Alzheimer’s and other forms of dementia.
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At this point in the progression of dementia, the neuropsych exam will yield more information about the type of dementia and how it is impacting her.
In the early days, imaging is more about eliminating things like tumors as a cause than pinpointing specific deficits and informing a definitive diagnosis. Additionally, the neuropsych is useful for teasing out the loss of very subtle skills, like spatial reasoning, needed for certain IADLs like driving and money management. Seeing this on paper can help a caregiver recognize what guardrails are needed and where.
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Just a note about the MRI imaging. There is brain shrinkage with Alz so an MRI is useful in helping with that diagnosis, however, not all dementia is ALz. I would also look at the medications that your DH is taking as some drugs cause brain fog. I hope that you get the info that you need.
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Thank you. Very helpful to better understand what we will walk away with after this assessment. Agree that it would be nice to know those critical areas impacted so I can plan ahead as best as possible.
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Good to know about the MRI.
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At our next appointment with the neurologist I will ask about a PET scan. Thank you
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For me, I found the cognitive testing to be validating for what I was actually seeing in him. My DH had poor short term memory and word retrieval issues as well as decreasing executive function. He scored in the 2 percentile for memory and word naming. He was “normal” in all other areas but he has a high cognitive reserve. The harder thing for me to deal with after the testing was that due to anosognosia he didn’t believe the results. I had naively thought that the results would help him see what I was seeing. It didn’t.
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Our Neuropsych testing result prompted a PETAmyloid scan. (They're worth the 4-5 hours and the exhausted LO afterwards. My DW was spent the whole next day afterwards… what the doc found in the neuropsych testing explained a lot.) The Gene test was positive for APOE4, fam history with AD on both sides of the fam, MRI Brain scan was "yer good. [a couple lil blank spots but nothing to think about]" PETAmyloid showed significant amyloid plaques & Neurologist made the Dx EOAD. DW (60 at the time of Dx, now 61). Referred us to USC, barely got started when insurance ended, took for-e-ver to get a referral to UCLA via medi-CAL. Before insurance spat us out, USC found deficits in an EEG, her MOCA was deficient, MRIBrain "mostly good, let's do the PETAmyloid [again]" but w/o insurance USC never did the PET. UCLA looked at everything, her MOCA was much lower than 6 months before at USC. For some obnoxious reason the original PETAmyloid scan that gave the Dx and the neuropsych test report were not in her file and I didn't have a disk with the images. Drove back to UCLA early this morning & they uploaded from the disk, I uploaded the neuropsych report, now waiting on the neuro to make a definitive Dx of EOAD (again… so she can finally get infusion therapy 7+ months later)… Neuro at UCLA left the Dx as Amnetic MCI pending her review of the original PETAmyloid scan. She's pretty sure she agrees with the original Neuro's Dx.
TLDR: basically, that Neuropsych report was the evidentiary catalyst that got to the PETAmyloid scan that produced the Dx of EOAD.1 -
Make sure you check for insurance coverage for the PET scan. It can be very expensive out of pocket. I have heard of cases where insurance does not cover the PET scan.
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After MCI diagnosis of Dementia-Possibly Vascular by the Neurologist at the VA, my DH had the Neuro-Psychologist test. It showed visuo-spatial difficulties and lack of executive function. The Psychologist's words that the test was "bizarre"… She said under no circumstances should he be driving. I was shocked. I had noticed he was driving very slowly but had no idea it was due to his dementia. She said that if he were to be in an accident, even if it wasn't his fault, we could be sued and lose everything. I sat my DH down and explained what the Psychologist said and the next day he gave me his keys. Never drove again. 18 months later his diagnosis was changed to Alzheimer's-Posterior Cortical Atrophy by the Neurologist. Dementia is more than memory loss. It's executive function:
Executive functions are the higher-level mental processes in the brain that act like an air traffic control system to help you plan, focus, remember instructions, and juggle multiple tasks.
Core Components
- Working memory: The ability to hold, update, and work with information in your mind over short periods.
- Inhibitory control: The self-control needed to resist impulses, ignore distractions, and think before you act.
- Cognitive flexibility: The capacity to switch gears, think outside the box, and adapt when plans change.
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Thank you for your reply. With the testing we’ve had thus far, my DH’s cognitive issues are executive function, communication and short term memory. He is still driving although he does not drive far nor much. He does drive extremely slowly, like 10 mph under the speed limit. We’ve discussed him no longer driving at some point.
I know that was a hard conversation for you & your DH to have but I’m glad you had it.0 -
Driving is one of the hardest discussions to have with someone with dementia. Dementia impacts safe driving. Your insurance company might not cover an accident leaving you open to getting sued for everything you own. What you described is not safe driving. Please, take the keys for the safety of your husband and everyone else who is near him while he is driving.
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Commonly Used Abbreviations
DH = Dear Husband
DW= Dear Wife, Darling Wife
LO = Loved One
ES = Early Stage
EO = Early Onset
FTD = Frontotemporal Dementia
VD = Vascular Dementia
MC = Memory Care
AL = Assisted Living
POA = Power of Attorney
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