From Michael Ellenbogen (via Lane): Alzheimer's Disease Drugs in Development 2023

Lane Simonian

This report on Alzheimer's drugs under development comes out annually. I believe that certain antioxidants provide the best chance of treating the disease. I counted 5 out of 187 drugs/natural products that act as antioxidants.

https://alz-journals.onlinelibrary.wiley.com/doi/10.1002/trc2.12385

Iris L.

What are the 5 antioxidant products from this study?

Lane Simonian

Beautiful, important question, Iris. I should have specified them in my originial post (I missed two of them while counting off the chart). They are:

Phase 3 Clinical Trials

Omega-3 (in fish oil and walnuts, for example),

Hydralozine-hydrochloride (used to treat high blood pressure),

Icosapent ethyl (a type of fish oil)

Phase 2 Clinical Trials

Edaravone (used to treat stroke and ALS)

DHA (a type of Omega-3 found in fish oil)

Flos Gossypii Flavonoids (derived from a flower of the same name)

Phase 1 Clinical Trial

CMS 121 (derivative of the flavanoid fisetin which can be found in strawberries among other fruits and vegetables)

I just noticed that only Hydralozine-hydrochloride and Flos Gossypii Flavanoids are the only ones being studied for mild to moderate Alzheimer's disease. The others are earlier interventions.

Iris L.

This is too complicated. The only ones I recognize are fish oil, walnut and strawberries, and a blood pressure medicine, which I am already eating and on. Flavanoids are in oranges. I have to keep things very simple for myself because my memory and cognition have been compromised. But thank you for responding, Lane.

Iris

Lane Simonian

All good choices, Iris.

inertia

https://alzconnected.org/discussion/comment/173382#Comment_173382

I agree it is not something a ad patient should not even attempt to read and understand that!