Good review article M1 receptor targeting
I came across this good review article from 2022 when I was looking for things to help my wife who is experiencing adverse effects from donepezil and rivastigmine.
It’s a good review article of the progress being made to develop drugs that have less adverse effects. Doesn’t look like anything is coming on the market anytime soon. But, if they can refine this class then there is potential for using them even in the severe stages to improve outcomes.
https://portlandpress.com/neuronalsignal/article/6/1/NS20210004/231109
Comments
-
One thing that’s frustrating, Vanderbilt University developed a compound VU319 but then licensed it to Acadia Pharmaceuticals and it seems like since then there’s been no word on it.
0 -
An article on Vanderbilt U and compound VU319. Mentions the Alzheimer’s Association Part the Cloud program
https://www.vumc.org/ccm/sites/default/files/VU319%20ARTICLE%20FROM%20VU.pdf
0
Commonly Used Abbreviations
DH = Dear Husband
DW= Dear Wife, Darling Wife
LO = Loved One
ES = Early Stage
EO = Early Onset
FTD = Frontotemporal Dementia
VD = Vascular Dementia
MC = Memory Care
AL = Assisted Living
POA = Power of Attorney
Read more
Categories
- All Categories
- 469 Living With Alzheimer's or Dementia
- 237 I Am Living With Alzheimer's or Other Dementia
- 232 I Am Living With Younger Onset Alzheimer's
- 14K Supporting Someone Living with Dementia
- 5.2K I Am a Caregiver (General Topics)
- 6.8K Caring For a Spouse or Partner
- 1.8K Caring for a Parent
- 156 Caring Long Distance
- 104 Supporting Those Who Have Lost Someone
- 11 Discusiones en Español
- 2 Vivir con Alzheimer u Otra Demencia
- 1 Vivo con Alzheimer u Otra Demencia
- 1 Vivo con Alzheimer de Inicio Más Joven
- 9 Prestación de Cuidado
- 2 Soy Cuidador (Temas Generales)
- 6 Cuidar de un Padre
- 22 ALZConnected Resources
- View Discussions For People Living with Dementia
- View Discussions for Caregivers
- Discusiones en Español
- Browse All Discussions
- Dementia Resources
- 6 Account Assistance
- 16 Help