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Questions about taking Donepezil Brand names: Aricept

Hi all,

I was diagnosed with ALZ a year ago at 62.

I have had several tests to rule out other possible problems. 2 Neurological Eeg test a year apart same results that show a large decline in my processing score.

My symptoms, of anxiety, mood swings, balance, memory are increasing.

I take mematine for memory and they Suggest I take Donepezil Brand names: Aricept, 

I typically have many side effects from medications.

Please please share your experience if you have or are taking this medication . Has it been helpful?

.thanks so much Barb

Comments

  • marionwilhelm
    marionwilhelm Member Posts: 13
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    I have no experience with those meds but will follow your progress eagerly.

  • allit
    allit Member Posts: 93
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    Hi,

    My wife is 65. She started on donepezil and felt it helped with focus and concentration. But she had a constant headache which went away when she stopped taking it.

    They switched her to rivastigmine. She’s had immediate side effects with that, horrible nausea and light sensitivity. Unfortunately we can’t switch to anything else right now because she’s starting Leqembi on Friday. If she wasn’t starting that we would switch to the patch form which may have less side effects. As far as memory issues go, I feel that she is doing better cognitively on that, easier to remember words and focus.

    There’s one more drug galantamine that is in the same class. But we haven’t tried that.

    And theres a new drug in that class due to come out next year. Zunveyl. It’s a different formulation of galantamine that is supposed to have less side effects.

  • David1946
    David1946 Member Posts: 772
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    I take those meds for almost a year with no side effects

  • Iris L.
    Iris L. Member Posts: 4,416
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    Welcome averyfam. I have been using Exelon patch and taking memantine for many years with no side effects.

    Iris

  • averyfam
    averyfam Member Posts: 4
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    Thanks for your help! My doctor is pretty conservative and doesn't recommend very many drugs!

  • averyfam
    averyfam Member Posts: 4
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    When you say many years that must mean you are doing well and things are progressing slowly!

    Barb

  • Iris L.
    Iris L. Member Posts: 4,416
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    Barb, my diagnosis is cognitive impairment not otherwise specified. From my Amyvid PET scan I was determined not to have Alzheimer's Disease. Nevertheless, I noticed improvement when I began using Exelon patch and Namenda, so I continue on these meds.

    Iris

  • Watson1
    Watson1 Member Posts: 22
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    I have been on doneprozol for over a year i find and return visits to the memory clinic have shown it is helping. we won't get miricals but some stability doesn't hurt. had some pretty good nightmares when i first started it but nothing in the scope of the alzheimer journey

  • David1946
    David1946 Member Posts: 772
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    edited October 5

    iI have also been on donepozol since my journey began about a year ago and it seems to be helping. I also had some real bad nightmares I would wake up screaming and yelling.

  • Watson1
    Watson1 Member Posts: 22
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    my lovely wife doesn't think to highly of the screening ,yelling nightmares

  • Iris L.
    Iris L. Member Posts: 4,416
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    David and Watson, do you think the nightmares might be related to watching scary television shows, such as crime dramas and even the nightly news shows or scary video games? I myself used to have disturbing dreams, and I traced them to television shows. I stopped watching television.

    Iris

  • David1946
    David1946 Member Posts: 772
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    IRIS L. My wife said try to stay away from scary t.v. shows. I try to watch mostly comedies.

  • Iris L.
    Iris L. Member Posts: 4,416
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    😄

  • averyfam
    averyfam Member Posts: 4
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  • Carl46
    Carl46 Member Posts: 160
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    Barb, my wife has taken memantine and donepezil since 2017. She has experienced no side effects. The meds were prescribed by her pcp when he diagnosed AD, and two neurologists have said this is the best regimen available. If your conservative doctor recommends donepezil, I think you should give it a try. You can always stop it if you have side effects.

  • David1946
    David1946 Member Posts: 772
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    I've been using Donepezil since I was diagnosed and it has helped me tremendously.

  • makking
    makking Member Posts: 18
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    edited October 12

    @David1946 , how long have you been using Donepezil?

    My DH was diagnosed in April this year with EO ALZ APOE 4/4 and has been taking 5mg Namenda (his tolerance) since June, with no real discernible "improvement". We transitioned to a new provider last week, a specialty geri neuro-psych team, who prescribed Aricept 5mg in addition to the Namenda, and the change in the past week has been dramatic - almost unnerving to me that the benefit could be so dramatic so quickly - literally, last week from what seemed to be Stage 4 and losing more function monthly to now functioning as if he was never ill. His energy, personality, wittiness, laughter, joking, and ability to understand innuendo has returned. It doesn't appear to be mania or aggression or hyperactivity. It's literally like my husband is just back with me.

    Frankly, I am confused and don't trust it. Does anyone else have input on dramatic improvements such as this, with medication starts? I don't expect that this is a miracle and that it's long-term. It's just a curious and unexpected happening, and I AM grateful for it, even if only temporary.

  • David1946
    David1946 Member Posts: 772
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    Marking, I have been taking Donepezil since I was diagnosed in November 2023 and ot has helped alot my nightmares and seeing ghost's (what my wife calls them my "Guardian Angels" have disappeared

  • Watson1
    Watson1 Member Posts: 22
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    i have alz. and have been on donpenizol- aricept it helps a lot. your husband may have hit an especially good day when he started the meds but that's fine. i find stability and that is good at this point. don't focus to much on meds or quick solutions. embrace the day with a little twist of alz. be good care partners and all will be zen

  • AlzWife2023
    AlzWife2023 Member Posts: 287
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    Try the patch. My husband is doing very well on it. He could not tolerate the pills.

  • ronda b
    ronda b Member Posts: 94
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    My DH is on ariceptand it seems to have helped him.

  • LindaOsw
    LindaOsw Member Posts: 3
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    I have Alzheimer’s with MCI and have been on doneprizil since May 2024. I felt nothing until sometime after the third week My thinking seemed suddenly clearer. It was kind is stunning. In trying to figure out what had changed I finally remember my new drug. I looked up information and was amazed to read that I was experiencing a known effect. I think it’s continuing to work for me. I also think it has suppressed my appetite. Among the things I’ve tried to do since my diagnosis is to get my weight in control. I’ve lost 35 pounds. I also realized that I am not very hungry so the weight loss has been easier than in the past. Linda

Commonly Used Abbreviations


DH = Dear Husband
DW= Dear Wife, Darling Wife
LO = Loved One
ES = Early Stage
EO = Early Onset
FTD = Frontotemporal Dementia
VD = Vascular Dementia
MC = Memory Care
AL = Assisted Living
POA = Power of Attorney
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